Originally Answered: white blood cells count and disease diagnosis?
I can provide with you with the necessary info but, my answer will be lengthy. I can provide info on WBC's and differential count.
Normal WBC count for an Adult/child>2 years: 5,000 - 10,000
Child<2 years: 6,200 - 17,000
Differential count: Measures the percentage of each type of leukocyte present in the same specimen.
Norrmal range values
Neutrophils: 55 -70
Lymphocytes: 20- 40
Monocytes: 2- 8
Interfering factors that may alter the results:
1) Physical activity and strees may cause an increase in WBC's and differential values
2) Pregnancy ( final month) and labor may cause increased WBC levels
3) Patients who have had a Splenectomy have a persistent, mild elevation of WBC counts
4) Drugs that may cause increased WBC levels include adrenaline,allopurinol,aspirin, chloroform, epinephrine, heparin,quinine, steriods, and triamterence(Dyrenium)
5) Drugs that cause decreased WBC levels includeantibiotics,anticonvulsants, antihistamines, antimetabolites, antithyroid meds, arsenicals, barbiturates, chemo agents, diuretics, and sulfonamides
1) infection 2) Leukemic neoplasia 3) Trauma 4) Stress 5) Tissue Necrosis 6) Inflammation
1) Drug toxicity (ie: chloramphenicol) 2) Bone marrow failure 3) Overwhelming infections 4) Dietary deficiency 5) Autoimmune disease ( Lupus) 6) Bone marrow infiltration ( myelofibrosis 7) Congenital marrow aplasia
The cause for abnormalities in the WBC and differential is quite a wide range of physical diseases/illnesses.Too numerous to mention. Maybe you can search the web to find out this additional information. Just type in WBC differential.
I hope that I was helpful. Here's a web: